{"id":867,"date":"2020-03-17T18:46:07","date_gmt":"2020-03-17T17:46:07","guid":{"rendered":"https:\/\/www.irbm.com\/?p=8439"},"modified":"2020-07-23T19:39:51","modified_gmt":"2020-07-23T17:39:51","slug":"piero-di-lorenzo-irbm-produced-the-first-batch-of-vaccines-la7-coffee-break-17th-march","status":"publish","type":"post","link":"https:\/\/www.cnccs.it\/en\/2020\/03\/17\/piero-di-lorenzo-irbm-produced-the-first-batch-of-vaccines-la7-coffee-break-17th-march\/","title":{"rendered":"Piero Di Lorenzo \u2013 IRBM produced the first batch of vaccines La7 Coffee Break \u2013 17th March"},"content":{"rendered":"[vc_row][vc_column][vc_video link=&#8221;https:\/\/youtu.be\/Lvs_615RN48&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][vc_text_separator title=&#8221;ENGLISH TRANSCRIPT&#8221; color=&#8221;sky&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<strong>PRESENTER<\/strong><\/p>\n<p>OK I\u2019ll go to Piero di Lorenzo straight away, meanwhile I\u2019ll pass on two bits of news: \u201cAuthorities in Germany have said that from today the infection risk is very high; in France, as a clear illustration of what is happening, the Lourdes Shrine has closed. So there is a total lockdown of everything. Prime Minister Conte also spoke a little while ago and reiterated that this is obviously a very difficult time and that Italy must show itself more united than ever before. So, Piero Di Lorenzo, Pomezia, on the outskirts of Rome, IRBM Science Park: you\u2019re working on a vaccine. We\u2019re speaking to you a couple of weeks on to find out what the situation is now. How is the work of your researchers going?<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>Yesterday we started producing the first batch of vaccines. Having characterized the adeno-virus and completed the related purification process, we started producing the vaccine. We expect to be ready by the end of May with the first doses to be used for the trials on mice. By the end of June, if the mice trials have not shown any toxicities or negative things, as we hope and expect, we are hopeful and optimistic that we can move on to humans.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>What does this mean? Once you get to the human trials, which, as Professor Vella and Di Lorenzo know very well, is divided into several stages, how long does this phase last?<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>The protocols require 3 clinical phases: 1, 2 and 3. Each of these 3 phases, according to the rules and the validated protocols, can last up to twelve or eighteen months. Obviously if the epidemic should become more worrying, if the situation should degenerate, the regulatory authorities may consider the need to shorten this time drastically.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>Yes.<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>Stefano Vella is well aware of how this works because he has experienced it first hand. I want to underline one thing: it\u2019s a pleasure to see a scientist on a television broadcast. It means that finally the era when \u201canyone who has read a newspaper article can pontificate\u201d is over and we\u2019re putting science first in every field: particularly in the field of biomedical science. Finally we have rediscovered the pleasure of listening to people who have studied all their lives to work on something rather than people who just talk drivel.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>Yes, you\u2019re right to underline it Piero Di Lorenzo, let\u2019s hope that even after the emergency is over, which we hope will happen as soon as possible, we\u2019ll continue to keep this firmly in our minds, not only because of how our national health service works and is working, thanks to everyone\u2019s self-sacrifice, and, making a quick foray into Stefano Vella\u2019s field, remember the importance of research, which is so mistreated in our country.<\/p>\n<p><strong>STEFANO VELLA<\/strong><\/p>\n<p>I am sure about one thing: this virus is no doubt a nasty creature. It is transmitted very quickly. It won\u2019t go away. We are trying to give it a clobbering. Doctors, nurses and ordinary people are trying to defeat it. People will be saved by research. It will save us because technologies have progressed. Many teams are working on drugs and vaccines. Remember AIDS? Drugs were eventually developed. They will come for this as well, and they\u2019ll save us. As I said, we need to be optimistic, this virus has now come between us.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>Do we have to learn to live with it?<\/p>\n<p><strong>STEFANO VELLA<\/strong><\/p>\n<p>Absolutely, this virus won\u2019t go back to where it came from, it is now one of our common germs.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>Yes, that\u2019s very clear.<\/p>\n<p><strong>STEFANO VELLA<\/strong><\/p>\n<p>So this virus will come back, it will be here. How do we suppress it? With the vaccine. There are many groups, including IRBM, that are famous for having produced lots of vaccines. Di Lorenzo is right. Remember the Ebola vaccine? It was made and deployed in a very short time. Objectively, while ensuring total safety for people, by shortening the timescale, a vaccine was fielded in a very short time. In fact the latest epidemic in the Democratic Republic of Congo was contained. I am sure that, and I say this to reassure people, while we have to stay strong because the situation is dramatic, and there are too many deaths, too many injured people, so we have to stay strong, I am sure that research, and I represent Italy in the European research program, has deployed&#8230; almost 500 million immediately through public tenders, and there are many European research institutions working together, in fact, as we have always hoped, collaboration is starting between the public and private sectors.\u00a0 Because this is the method that will work.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>This collaboration is crucial in every area of our lives, because otherwise&#8230;<\/p>\n<p><strong>STEFANO VELLA<\/strong><\/p>\n<p>In research above all, because there is a lot of academic research, which has to work with industrial research, which is where things are developed. If this collaboration works, that is what will ultimately save us from future problems.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>So I want to say goodbye to Piero Di Lorenzo pointing out that&#8230;<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>I\u2019m sorry&#8230;<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>Go ahead.<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>I\u2019m sorry, I\u2019d like to add something to what Stefano Vella said, because I feel it is very important. Yesterday and today, many newspapers reminded us of a speech given by Bill Gates four years ago in which he envisaged that: The next war won\u2019t be against an enemy with missiles, but against viruses. That\u2019s where we are now, unfortunately we didn\u2019t listen to him enough. In this respect I would like you file one piece of news in your memory bank. Three years ago there was a Zika epidemic in Lazio, only one person was infected after being stung by a mosquito. This caused a massive state of alarm. Commendably and bravely, Governor Zingaretti, together with Vice President Smeriglio, took steps to launch a research program and, with a public-private consortium, going back to what Vella was saying earlier, research into the Zika virus started. We worked as part of this consortium for the Zika virus and viruses in the same family for 2 years. The newspapers engaged in an idiotic controversy, saying that: \u201cThe virus was in Brazil and the Lazio Region is wasting money from Lazio\u2019s taxpayers to do the research\u201d. The Zika virus might be in Brazil but it doesn\u2019t need a passport to come to Italy and Europe&#8230;<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>We realized this, and how!<\/p>\n<p><strong>PIERO DI LORENZO<\/strong><\/p>\n<p>If something happens, God forbid, remember that the funding ends in June. That research will not be funded again, I\u2019m sure about that, because of the controversy in the press. Pull out this bit of the broadcast when, God forbid, this happens.<\/p>\n<p><strong>PRESENTER<\/strong><\/p>\n<p>No, no, let\u2019s hope not. We already have our hands full with the Coronavirus. So thank you to Piero Di Lorenzo. Good luck of course to you and all the IRBM researchers in your work.[\/vc_column_text][\/vc_column][\/vc_row]","protected":false},"excerpt":{"rendered":"<p>vc_rowvc_columnvc_video link=&#8221;https:\/\/youtu.be\/Lvs_615RN48&#8243;\/vc_column\/vc_rowvc_rowvc_columnvc_text_separator title=&#8221;ENGLISH TRANSCRIPT&#8221; color=&#8221;sky&#8221;\/vc_column\/vc_rowvc_rowvc_columnvc_column_textPRESENTER OK I\u2019ll go to Piero di Lorenzo straight away, meanwhile I\u2019ll pass on two bits of news: \u201cAuthorities in Germany have said that from today the infection risk is very high; in France, as a clear illustration of what is happening, the Lourdes Shrine has closed. So there is a &hellip;<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"video","meta":{"footnotes":""},"categories":[18],"tags":[],"class_list":["post-867","post","type-post","status-publish","format-video","hentry","category-galleria","post_format-post-format-video"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Piero Di Lorenzo \u2013 IRBM produced the first batch of vaccines La7 Coffee Break \u2013 17th March - CNCCS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cnccs.it\/en\/2020\/03\/17\/piero-di-lorenzo-irbm-produced-the-first-batch-of-vaccines-la7-coffee-break-17th-march\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Piero Di Lorenzo \u2013 IRBM produced the first batch of vaccines La7 Coffee Break \u2013 17th March - CNCCS\" \/>\n<meta property=\"og:description\" content=\"vc_rowvc_columnvc_video link=&#8221;https:\/\/youtu.be\/Lvs_615RN48&#8243;\/vc_column\/vc_rowvc_rowvc_columnvc_text_separator title=&#8221;ENGLISH TRANSCRIPT&#8221; color=&#8221;sky&#8221;\/vc_column\/vc_rowvc_rowvc_columnvc_column_textPRESENTER OK I\u2019ll go to Piero di Lorenzo straight away, meanwhile I\u2019ll pass on two bits of news: \u201cAuthorities in Germany have said that from today the infection risk is very high; in France, as a clear illustration of what is happening, the Lourdes Shrine has closed. 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CNCCS","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cnccs.it\/en\/2020\/03\/17\/piero-di-lorenzo-irbm-produced-the-first-batch-of-vaccines-la7-coffee-break-17th-march\/","og_locale":"en_US","og_type":"article","og_title":"Piero Di Lorenzo \u2013 IRBM produced the first batch of vaccines La7 Coffee Break \u2013 17th March - CNCCS","og_description":"vc_rowvc_columnvc_video link=&#8221;https:\/\/youtu.be\/Lvs_615RN48&#8243;\/vc_column\/vc_rowvc_rowvc_columnvc_text_separator title=&#8221;ENGLISH TRANSCRIPT&#8221; color=&#8221;sky&#8221;\/vc_column\/vc_rowvc_rowvc_columnvc_column_textPRESENTER OK I\u2019ll go to Piero di Lorenzo straight away, meanwhile I\u2019ll pass on two bits of news: \u201cAuthorities in Germany have said that from today the infection risk is very high; in France, as a clear illustration of what is happening, the Lourdes Shrine has closed. 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